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Principles of Biochemistry by Harvard University

posted Jul 30, 2015, 6:27 AM by Dilan Rostam   [ updated Jul 30, 2015, 6:39 AM ]
This introduction to biochemistry explores the molecules of life, starting at simple building blocks and culminating in complex metabolism.
About this course

Principles of Biochemistry integrates an introduction to the structure of macromolecules and a biochemical approach to cellular function. Topics addressing protein function will include enzyme kinetics, the characterization of major metabolic pathways and their interconnection into tightly regulated networks, and the manipulation of enzymes and pathways with mutations or drugs. An exploration of simple cells (red blood cells) to more complex tissues (muscle and liver) will be used as a framework to discuss the progression in metabolic complexity. Learners will also develop problem solving and analytical skills that are more generally applicable to the life sciences.
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Image credit: PDB ID 2DN1, 2DN2

Image credit: PDB ID 2DN1, 2DN2

Park S-Y, Yokoyama T, Shibayama N, Shiro Y, Tame JRH (2006) 1.25 A resolution crystal structures of human haemoglobin in the oxy, deoxy and carbonmonoxy forms. J Mol Biol 360: 690–701.

What you'll learn
  • The structure and function of the chemical building blocks of life
  • How to navigate protein structures using PyMOL
  • The central role of enzymes in catalyzing the reactions of life
  • The primary metabolic pathways that power cells
  • The intricate mechanisms that regulate cellular metabolism
  • The integration of biochemical processes in the context of cells, tissues, and whole organisms

Meet the instructors

  • bio for Alain Viel

    Alain Viel

    Senior LecturerDepartment of Molecular and Cellular Biology at Harvard University

  • bio for Rachelle Gaudet

    Rachelle Gaudet

    Professor of Molecular and Cellular BiologyHarvard University

Please note these course are represented and linked for extra help for you. You can enrol